Nurofen for Children Special Precautions

Nurofen for Children should be given with care to the elderly, to patients with cardiovascular disease, and in liver or renal failure. Patients with congestive heart failure, cirrhosis, diuretic-induced volume depletion, or renal insufficiency require local synthesis of vasodilating prostaglandins to maintain renal perfusion, and therefore these patients are at greater risk of developing renal dysfunction due to NSAID-induced inhibition of renal prostaglandin synthesis.
Nurofen for Children should be discontinued in patients who experience blurred or diminished vision, or changes in colour vision. Patients with collagen disease may be at increased risk of developing aseptic meningitis.
Nurofen for Children should be given with care to patients who have asthma or have ever suffered from asthma.
If the child's symptoms (eg, earache) persist for >3 days, consult the doctor.
Nurofen for Children should be given with care to patients with systemic lupus erythematosus and mixed connective tissue disease, history of gastrointestinal disease (ulcerative colitis, Crohn’s disease). Use in pregnancy & lactation: Whilst no teratogenic effects have been demonstrated in animal experiments, the use of ibuprofen during pregnancy should, if possible, be avoided. In the limited studies so far available, ibuprofen appears in the breast milk in very low concentration and is unlikely to affect the breastfed infant adversely.